B.S in Biology, Nanjing University, Nanjing, China (2003.9-2007.7)
Ph.D. in Neuroscience, Institute of Neuroscience, Chinese Academy of Sciences, Shanghai, China (2007.9-2013.3)
2013.4 - 2019.7 Postdoctoral fellow, Catherine Dulac lab, HHMI, Harvard University, USA
2019.8 – present Assistant Investigator, Chinese Institute for Brain Research, CIBR, Beijing, China
2018 Harvard Chinese Life Science Annual Distinguished Research Award
2014-2017 Human Frontier Science Program, Long-term Postdoc Fellowship
2013 Chinese Academy of Sciences presidential prize
2013 Ray Wu prize
A long-sought goal in neuroscience is to understand how the nervous system interprets salient information from the external world and generate appropriate behaviors. In social environments, individual interests may be conflicted with the needs and expectations of others. Thus, the ability to respond adequately to social stimuli is critical for facilitating adaptive behaviors that are directed at increasing reproduction and survival. Although most animals are capable of adjusting social behaviors depending on their internal states and the expectations of encounters, we are only beginning to understand the underlying neural circuits and mechanisms that mediate the formation and the plasticity of adaptive social behaviors. Combining multi-disciplinary approaches including microendoscope-based calcium imaging, single-cell sequencing, optogenetics, photometry, in vivo and ex vivo electrophysiology and pharmacology approaches, my laboratory aims to understand the underlying neural circuits that mediate the processing of environmental social stimuli.
Where are the neurons specifically involved in coordinating changes of internal states to generate adaptive behavioral responses? Which neural circuits are responsible for assigning emotional values (i.e., positive and negative) to environmental social cues? How are these circuits regulated by the activity of multiple neuromodulation systems? Whether individuals perceive themselves and others differently in young and adult? If so, what is the developmental trajectory and how does it shape by experience? Answering these questions will enable us to understand the nature of neural circuit dynamics that contribute to adaptive behaviors and lead to the development of novel treatments to social deficits in neuropsychiatric disorders.