Nature Communications | Multiplicative Joint Coding in Preparatory Activity for Reaching Sequence in Macaque Motor Cortex | He Cui Lab
The He Cui Laboratory at the Chinese Institute for Brain Research (CIBR) published a research atricel titled “Multiplicative Joint Coding in Preparatory Activity for Reaching Sequence in Macaque Motor Cortex” in Nature Communications on April 11, 2024. The study reveals that the motor cortex neuron can encode interacive components of movement elements in a sequence during preparation. Regression anaylsis sugguests a transformed coding mechnism from multiplicative coding during motor preparation to additive coding during motor execution. These findings suggest that sequential movement is encoded neither in integrative or independent manner in motor cortex but in different ways in different epochs. This study applied the dynamical systems view at the neural coding level, indicates that the population function changes as temporal evolution. Understanding of the coding mechanism may help building decoders for complex movement and refined BMI system.
