Research Groups Collaborating Core Facilities

Ying Fang

Investigator
Ph.D.
Neural Circuit Mechanisms of Motor Control and Next-Generation Brain-Computer Interface Technology
fangying@cibr.ac.cn
Education Experience

1997 - 2002 B.S. in Chemistry, University of Science and Technology of China

2002 - 2007 Ph.D. in Chemistry, Harvard University

Professional Experience

2007-2008     Postdoc, Harvard University

2008-2024     Investigator, National Center for Nanoscience and Technology, China

2022-2024     Jointly Appointed Investigator, Chinese Institute for Brain Research, Beijing

2024-present   Investigator, Chinese Institute for Brain Research, Beijing


Research Description

Disrupted functions for motor control in the brain are associated with various diseases, including Parkinson's disease. Studying how the brain generates complex motor control can not only reveal its neural circuit mechanisms but also provide important insights for technologies such as neuromodulation and brain-computer interfaces (BCIs). Neuromodulation techniques can treat neurological diseases by regulating neural circuit activities, while BCIs can translate brain signals into machine commands to help paralyzed patients regain motor control. Our lab investigates the neural mechanisms of motor control in animal models, including mice and non-human primates. We are also committed to developing neural activity recording and modulation techniques to provide new technical tools for basic neuroscience research and to promote the development of next-generation BCIs.

Publications

1. Shouliang Guan#, Huihui Tian#, Yinan Yang#, Mengcheng Liu, Jianfei Ding, Jinfen Wang, Ying Fang*. Self-assembled ultraflexible probes for long-term neural recordings and neuromodulation. Nature Protocols, 2022, 18, 1712

2. Liang Zou#, Huihui Tian#, Shouliang Guan, Jianfei Ding, Lei Gao, Jinfen Wang, Ying Fang*. Self-assembled multifunctional neural probes for precise integration of optogenetics and electrophysiology. Nature Communications, 2021, 12, 5871.

3. Lei Gao#, Jinfen Wang#, Yan Zhao#, Hongbian Li, Mengcheng Liu, Jianfei Ding, Huihui Tian, Shouliang Guan, Ying Fang*. Free-standing nanofilm electrode arrays for long-term stable neural interfacings. Advanced Materials, 2022, 34(5), 2107343.

4. Shouliang Guan#, Jinfen Wang#, Xiaowei Gu#, Yan Zhao, Ruiqing Hou, Hongmei Fan, Liang Zou, Lei Gao, Mingde Du, Chengyu Li*, Ying Fang*. Elastocapillary self-assembled neurotassels for stable neural activity recordings. Science Advances, 2019, 5(3), eaav2842.

5. Jia Liu#, Tianming Fu#, Zengguang Cheng#, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter Kruskal, Chong Xie, Zhigang Suo, Ying Fang*, Charles M. Lieber*. Syringe-injectable electronics. Nature Nanotechnology, 2015, 10 (7), 629-636.