Synthesis Assistant (Organic Synthesis) Opportunities：Join the Medicinal Chemistry Center at CIBR.

About Medicinal Chemistry Center (MCC)

The MCC is one of the 11 core facilities of CIBR, located at the west end of the 6th floor in Building B of CIBR Phase II, with approximately 350 square meters of laboratory space. The lab is equipped with 23 fume hoods, including 2 walk-in fume hoods.

MCC provides in-depth knowledge of modern concepts in drug discovery and medicinal chemistry technology, including structure-activity relationships (SAR) of CNS bioactive molecules, rational CNS drug design and evaluation, and the preclinical and early clinical drug discovery process, which includes target identification, hit and lead optimization, candidate selection, preclinical development, and Phase I clinical studies planning. MCC also covers modern concepts in drug discovery, such as property- and structure-based drug design, fragment-based drug discovery, in silico methods, and ADME-T principles.

For more information, please visit https://medchem.cibr.ac.cn/?language=cn#/home

Position: Synthesis Assistant (Organic Synthesis)

Job Description:

Synthesize designated compounds and assist in research projects.

Qualifications:

1. Bachelor's or Master's degree with 1-5 years of experience in organic synthesis at a CRO or pharmaceutical company.

2. Proficient in using Scifinder or Reaxys database for literature searches and capable of independently designing preliminary synthetic routes for target compounds.

3. Skilled in independently conducting chemical experiments, with experience in anhydrous and oxygen-free operations, catalytic hydrogenation, preparation and use of Grignard reagents, and free radical reactions (including operation, workup, and purification).

4. Familiar with common organic reaction mechanisms; able to analyze reaction issues and propose solutions based on experimental results.

5. Capable of troubleshooting experimental problems and independently managing moderately complex research projects.

6. Meticulous in maintaining clear and complete experimental records and reports.

Application Method:

Interested candidates should send their resume, contact information, and relevant application materials to zhenghanyu@cibr.ac.cn and liweijian@cibr.ac.cn.

Please use "Application for Organic Synthesis Position + Your Name" as the email subject.

All applications will be kept strictly confidential.